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Credit: CC0 Public Domain In a brand-new study from the University at Buffalo, researchers discovered that people with Type 2 diabetes who were prescribed SGLT2 inhibitors lost more weight than patients who got GLP-1 receptor agonists. The study sought to evaluate the difference in weight loss triggered by the antidiabetic medicationsboth of which work to manage blood sugar level levels.

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5 pounds. Weight-loss is an important quality for diabetic medications as being obese is a common attribute of the disease, and can eventually lead to reduced insulin level of sensitivity. With weight reduction, it is possible to gain back insulin sensitivity, enhance glucose control, and reduce heart danger factors and comorbidities. Both SGLT2 inhibitors and GLP-1 receptor agonists are advised as second-line treatments for Type 2 diabetes after the use of metformin, a drug also recommended to manage blood sugar level, says Albanese.

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The researchers determined weight-loss after six months of successive therapy, and differences in blood pressure, blood glucose levels and kidney function. Canagliflozin, sold under the brand name Invokana, was the most typically recommended SGLT2 inhibitor. Liraglutide, sold under the brand name Victoza, was the most frequently recommended GLP-1 receptor agonist.

But SGLT2 inhibitors are more protective against weight gain triggered by other antidiabetic drugs than GLP-1 receptor agonists. The results counter previous research study that has discovered GLP-1 receptor agonists to be the remarkable antidiabetic drug for weight-loss, The group says these medications at dosages approved for treating Type 2 diabetes are not planned for weight-loss.

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One author of the research study is Nicole Paolini Albanese, Pharm, D.Copyright 2021 Knowridge Science Report.  Learn More Here  booked.